Anti-DKFZP434N0250, Anti-PKBG, Anti-PRKBG, Anti-RACgamma, Anti-RACPKgamma, Anti-STK2, Anti-v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
- русский язык имя
- английское имяAnti-DKFZP434N0250, Anti-PKBG, Anti-PRKBG, Anti-RACgamma, Anti-RACPKgamma, Anti-STK2, Anti-v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
- CAS №
- CBNumberCB72099524
- мольный вес0
- файл MolMol file
Anti-DKFZP434N0250, Anti-PKBG, Anti-PRKBG, Anti-RACgamma, Anti-RACPKgamma, Anti-STK2, Anti-v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) химические свойства, назначение, производство
Общее описание
AKT serine/threonine kinase 3 (AKT3) is part of the protein kinase B family. It has a kinase domain, a pleckstrin homology domain and a regulatory domain. The protein consists of 479 amino acids and the gene encoding it is localized on human chromosome 1q44.Биохимия/физиол Действия
AKT serine/threonine kinase 3 (AKT3) has a role in DNA repair and brain development. In mouse model, it modulates the expression of estrogen receptor α, Erb-B2 receptor tyrosine kinase 2 and Erb-B2 receptor tyrosine kinase 3 in breast cancer cells. AKT3 has been shown to stimulate the growth of triple-negative breast cancer.