D-gamma-Tocotrienol
- русский язык имя
- английское имяD-gamma-Tocotrienol
- CAS №14101-61-2
- CBNumberCB71241238
- ФормулаC28H42O2
- мольный вес410.63
- номер MDLMFCD00901547
- файл Mol14101-61-2.mol
химическое свойство
| Температура кипения | 530.8±49.0 °C(Predicted) |
| плотность | 0.964±0.06 g/cm3(Predicted) |
| температура хранения | −20°C |
| растворимость | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| пка | 11.05±0.40(Predicted) |
| форма | Liquid |
| цвет | Very Dark Yellow |
| Биологические источники | Elaeis guineensis |
| Стабильность | Light Sensitive |
| LogP | 10.300 (est) |
| FDA UNII | 185QAE24TR |
| UNSPSC Code | 85151701 |
| NACRES | NA.24 |
D-gamma-Tocotrienol химические свойства, назначение, производство
Описание
γ-Tocotrienol is a form of vitamin E that has been found in rice bran and has diverse biological activities. It reduces cell death induced by hydrogen peroxide, paraquat, S-nitrocysteine, SIN-1 , or L-buthionine-(S,R)-sulfoximine (BSO; ) in rat striatal cultures when used at concentrations ranging from 0.1 to 10 μM. γ-Tocotrienol (20 μM) induces apoptosis in malignant sympathoadrenal (+SA) mouse mammary epithelial cells. In vivo, γ-tocotrienol (15, 30, and 150 mg/kg) reduces blood pressure and plasma lipid peroxide levels in spontaneously hypertensive rats. [Matreya, LLC. Catalog No. 2111]Химические свойства
g:d:aTocotrienol 1.6:0.4:1Использование
γ-Tocotrienol exhibits antioxidant properties and belongs to the vitamin E family. It is naturally found in wheat germ oil and bran. In addition, α-tocopherol and γ-tocotrienol derivatives are potential lead compounds for developing?anticancer and?antiproliferative agents against?MCF-7 and MDA-MB-231 breast cancer cells and the A549 lung cancer cells.Определение
ChEBI: A tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2, 7 and 8 and a farnesyl chain at position 2.D-gamma-Tocotrienol поставщик
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