Epothilone A
- русский язык имя
- английское имяEpothilone A
- CAS №152044-53-6
- CBNumberCB6972280
- ФормулаC26H39NO6S
- мольный вес493.66
- номер MDLMFCD26960884
- файл Mol152044-53-6.mol
химическое свойство
| Температура плавления | 95℃ |
| альфа | D21 -47.1° (c = 1.0 in methanol) |
| Температура кипения | 683.3±55.0 °C(Predicted) |
| плотность | 1.143 |
| температура хранения | -20°C |
| растворимость | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| пка | 13.57±0.70(Predicted) |
| форма | solid |
| цвет | White to Off-White |
| Стабильность | Stable under recommended storage conditions., Stable Under Recommended Storage C |
| ИнЧИКей | HESCAJZNRMSMJG-KKQRBIROSA-N |
| SMILES | [C@]12([H])[C@]([H])(O1)CCC[C@H](C)[C@H](O)[C@@H](C)C(=O)C(C)(C)[C@@H](O)CC(=O)O[C@H](/C(/C)=C/C1=CSC(C)=N1)C2 |
| FDA UNII | 51E07YBX96 |
Epothilone A химические свойства, назначение, производство
Использование
The epothilones are a novel class of antineoplastic agents possessing antitubulin activity. Epothilone A, B isolated from Sorangium cellulosum was associated with cell cycle arrest at G2/M transition and apoptosis that was resisted with overexpression of β-tubulin and P-glycoprotein in human bladder carcinoma cell.Определение
ChEBI: An epithilone that is epothilone C in which the double bond in the macrocyclic lactone ring has been oxidised to the corresponding epoxide (the 13R,14S diastereoisomer).Epothilone A поставщик
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