Epothilone A
- русский язык имя
- английское имяEpothilone A
- CAS №152044-53-6
- CBNumberCB6972280
- ФормулаC26H39NO6S
- мольный вес493.66
- номер MDLMFCD26960884
- файл Mol152044-53-6.mol
химическое свойство
Температура плавления | 95℃ |
альфа | D21 -47.1° (c = 1.0 in methanol) |
Температура кипения | 683.3±55.0 °C(Predicted) |
плотность | 1.143 |
температура хранения | -20°C |
растворимость | Chloroform (Slightly), Ethyl Acetate (Slightly) |
пка | 13.57±0.70(Predicted) |
форма | solid |
цвет | White to Off-White |
Стабильность | Stable under recommended storage conditions., Stable Under Recommended Storage C |
FDA UNII | 51E07YBX96 |
Epothilone A химические свойства, назначение, производство
Использование
The epothilones are a novel class of antineoplastic agents possessing antitubulin activity. Epothilone A, B isolated from Sorangium cellulosum was associated with cell cycle arrest at G2/M transition and apoptosis that was resisted with overexpression of β-tubulin and P-glycoprotein in human bladder carcinoma cell.Определение
ChEBI: An epithilone that is epothilone C in which the double bond in the macrocyclic lactone ring has been oxidised to the corresponding epoxide (the 13R,14S diastereoisomer).Epothilone A поставщик
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