Parecoxib
- русский язык имя
- английское имяParecoxib
- CAS №1709956-95-5
- CBNumberCB6951641
- ФормулаC16H12ClNO3S
- мольный вес333.79
- файл Mol1709956-95-5.mol
химическое свойство
| Температура плавления | 165-167°C |
| Температура кипения | 459.4±45.0 °C(Predicted) |
| плотность | 1.340±0.06 g/cm3(Predicted) |
| температура хранения | Refrigerator |
| растворимость | DMSO (Slightly), Methanol (Slightly) |
| пка | -3.44±0.50(Predicted) |
| форма | Solid |
| цвет | White to Off-White |
| FDA UNII | 9TUW81Y3CE |
| Код УВД | M01AH04 |
Parecoxib химические свойства, назначение, производство
Использование
3-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonyl Chloride is an Impurity of Parecoxib Sodium (P193275), an anti-inflammatory, analgesic.Клиническое использование
Parecoxib is a pro-drug of valdecoxib administered IM or IV for perioperative analgesic and anti-inflammatory use. As a pro-drug, it undergoes rapid in vivo hydrolysis to valdecoxib.Parecoxib at greater than 20 mg has analgesic activity superior to that of placebo and similar to that of parenteral 30 or 60 mg of ketorolac in patients with postoperative dental pain. A significant adverse effect is drug hypersensitivity. Parecoxib is currently marketed worldwide but has not been approved for use in the United States.Parecoxib поставщик
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