Z-DEVD-FMK
- русский язык имя
- английское имяZ-DEVD-FMK
- CAS №210344-95-9
- CBNumberCB6453635
- ФормулаC30H41FN4O12
- мольный вес668.66
- номер MDLMFCD23380217
- файл MolMol file
химическое свойство
Температура кипения | 914.2±65.0 °C(Predicted) |
плотность | 1.260±0.06 g/cm3(Predicted) |
температура хранения | Inert atmosphere,Store in freezer, under -20°C |
растворимость | DMSO/DMF: ≥20 mM |
пка | 10.26±0.46(Predicted) |
форма | White to slightly brown solid |
цвет | White to off-white |
Z-DEVD-FMK химические свойства, назначение, производство
Использование
Z-DEVD-FMK is an irrversible caspase-3 inhibitor used as an anaesthetic agent. In addition, it is proposed to increase the longevity of platelet storage.Общее описание
A potent, cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, caspase-7, caspase-8, and caspase-10. When using with purified native or recombinant enzyme, pretreatment with an esterase is required. A 5 mM (250 μg/75 μl) solution of Z-DEVD-FMK (Cat. No. 264156) in DMSO is also available.Биологическая активность
Cell-permeable, irreversible inhibitor of caspase-3/CPP32; inhibits tumor cell apoptosis. Neuroprotective in rat hippocampus following seizures in vivo .Z-DEVD-FMK поставщик
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