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![S-(5′-Adenosyl)-L-methionine chloride dihydrochloride структурированное изображение](/CAS/20150408/GIF/86867-01-8.gif)
S-(5′-Adenosyl)-L-methionine chloride dihydrochloride
- английское имяS-(5'-Adenosyl)-L-Methionine chloride dihydrochloride
- CAS №86867-01-8
- CBNumberCB62655576
- ФормулаC15H24Cl2N6O5S
- мольный вес471.35
- EINECS246-184-8
- номер MDLMFCD22571809
- файл Mol86867-01-8.mol
химическое свойство
температура хранения | -20°C |
растворимость | H2O: soluble100mg/mL |
форма | A lyophilized powder |
цвет | Off-white to light yellow |
БРН | 6560002 |
Коды опасности | Xn |
Заявления о рисках | 20/21/22-68/20/21/22 |
Заявления о безопасности | 36-45 |
WGK Германия | 3 |
S-(5′-Adenosyl)-L-methionine chloride dihydrochloride химические свойства, назначение, производство
Описание
S-Использование
S-(5′-Adenosyl)-L-methionine chloride dihydrochloride has been used as a medium supplement for S30 cell extract. It also has been used for measuring the interaction with catechol-O-methyltransferase (COMT) by quartz crystal microbalance (QCM), surface plasmon resonance (SPR) and isothermal titration calorimetry (ITC) with supported lipid bilayers and vesicles.Общее описание
S-(5′-Adenosyl)-L-methionine chloride dihydrochloride (SAM) facilitates the transfer of methyl groups to proteins, lipids and nucleic acids. Methionine adenosyl transferase catalyses the synthesis of SAM from methionine and adenosine triphosphate (ATP). SAM functions to regulate various cellular functions like cell division, cell death, transcription, genetic stability, oxidant/antioxidant balance and polyamine homeostasis. Therapeutically, SAM finds its application as a nutritional supplement in humans for various diseases like osteoarthritis and liver injury. SAM also regulates transsulfuration reactions by binding to the regulatory domain of key enzyme cystathionine-β-synthase (CBS).S-(5′-Adenosyl)-L-methionine chloride dihydrochloride поставщик
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