N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE
- русский язык имя
- английское имяN-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE
- CAS №80376-66-5
- CBNumberCB6160140
- ФормулаC10H24N2Si
- мольный вес200.4
- номер MDLMFCD00272687
- файл Mol80376-66-5.mol
химическое свойство
| Температура кипения | 78-80 °C (7 mmHg) |
| показатель преломления | 1.45-1.452 |
| температура хранения | 0-6°C |
N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE химические свойства, назначение, производство
Химические свойства
CLEAR PALE YELLOW LIQUIDИспользование
N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE conveniently effects the transformation of ketones and aldehydes to homologated nitriles, amines, aldehydes, and ketones.Синтез
N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE is easily synthesized by a two-step procedure (eq 1).1 Initially, the condensation of t-Butylamine with either N,N-Dimethylformamide or dimethylformamide dimethyl acetal cleanly affords N′-t-Butyl-N,N-dimethylformamidine. Subsequent lithiation and silylation with Chlorotrimethylsilane results in a 70% overall yield of the purified title reagent.
хранилище
The reagent should be handled in a fume hood. Refrigeration should be used for prolonged storage.