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propylhexedrine
- русский язык имя
- английское имяpropylhexedrine
- CAS №3595-11-7
- CBNumberCB5914315
- ФормулаC10H21N
- мольный вес155.28044
- EINECS222-741-0
- файл Mol3595-11-7.mol
химическое свойство
Температура кипения | bp760 205°; bp20 92-93° |
плотность | d425 0.8501 |
показатель преломления | nD20 1.4600 |
пка | pKa 10.52(H2O,t =25±0.2,I≤0.001) (Uncertain) |
FDA 21 CFR | 341.20 |
FDA UNII | LQU92IU8LL |
propylhexedrine химические свойства, назначение, производство
Использование
Adrenergic (vasoconstrictor).Всемирная организация здравоохранения(ВОЗ)
Propylhexedrine, a sympathomimetic amine, has been widely available since 1949 in over-the-counter inhalants for nasal decongestion and in oral anorexic preparations. As dependence can occur and because abuse has been reported, propylhexedrine was subjected in 1986 to control under Schedule IV of the 1971 Convention on Psychotropic Substances. (Reference: (WHTAC2) 2nd Report of the WHO Expert Committee on Drug Dependence (IV), 729, , 1985)Общее описание
Propylhexedrine is another analog ofamphetamine in which the aromatic ring has been replacedwith a cyclohexane ring. This drug produces vasoconstrictionand a decongestant effect on the nasal membranes, butit has only about one half the pressor effect of amphetamineand produces decidedly fewer effects on the CNS. Its majoruse is for a local vasoconstrictive effect on nasal mucosa inthe symptomatic relief of nasal congestion caused by thecommon cold, allergic rhinitis, or sinusitis.