Циннамoнитрил

Химические свойства

Clear colourless to yellow liquid, ractical}y insoluble in water, soluble in alcohol and oils.

Вхождение

Has apparently not been reported to occur in nature.

Использование

Cinnamonitrile is a parent compound whose derivatives can be applied as corrosion inhibitors for API J55 steel.

Подготовка

From styryl bromide and potassium cyanide (Arctander, 1969).

Метаболизм

The toxicity of organic cyanides appears to depend almost entirely on whether they can be metabolized in the body to the free cyanide ion, and on the rate and extent of this conversion and the rate of detoxication of cyanide to thiocyanate. In general, alkyl and arylalkyl cyanides are metabolized with the formation of hydrogen cyanide, while the nitrile group of aryl cyanides is relatively stable. The high toxicity of iv-administered cinnamyl nitrile and the rapidity of death suggest that in rabbits this compound is metabolically converted to hydrogen cyanide (Hunt, 1923; Williams, 1959).