Wild Yam Extract

Определение

Wild yam is a plant promoted as natural DHEA because it contains diosgenin, which can be used in the lab to create estrogen and DHEA. The extract obtained from Dioscorea Villosa (Wild Yam) roots. Contains 20% extract dissolved in water and glycerin. Has soothing, calming, and purifying properties[1].

разработк И противоопухолевых препаратов

Research on the medicinal value of wild yam root extract (WYE) has shown evidence suggesting anticancer properties, particularly for breast cancer and in both hormone receptor-positive and triple-negative breast cancers (TNBC), where it alters epigenetic 5-hydroxymethylcytosine DNA patterns, induces toxicity, halts cell cycle, inhibits fatty acid synthase and modifies the activity of estrogen and progesterone hormone receptors. WYE contains hundreds of constituent saponins such as deltonins, dioscoreavillosides, diarylheptanoids, diosgenin, and dioscin; the latter two alone can slow breast tumor growth and migration, deter stem cell phenotype and cause cell death in various models[2].