(2R,3S)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride
- русский язык имя
- английское имя(2R,3S)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride
- CAS №1185503-48-3
- CBNumberCB52669000
- ФормулаC20H18F7NO2
- мольный вес437.35
- EINECS-0
- файл Mol1185503-48-3.mol
химическое свойство
| Температура кипения | 387.9±42.0 °C(Predicted) |
| плотность | 1.37±0.1 g/cm3(Predicted) |
| пка | 6.93±0.60(Predicted) |
(2R,3S)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride химические свойства, назначение, производство
Использование
Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1''R)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.(2R,3S)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride поставщик
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