5-БЕНЗИЛИДЕНГИДАНТОИН
- английское имя5-Benzylidenehydantoin
- CAS №3775-01-7
- CBNumberCB5179770
- ФормулаC10H8N2O2
- мольный вес188.18
- номер MDLMFCD00014494
- файл Mol3775-01-7.mol
химическое свойство
| Температура плавления | 220.00°C - 222.00°C |
| плотность | 1.329g/cm3 |
| InChI | InChI=1S/C10H8N2O2/c13-9-8(11-10(14)12-9)6-7-4-2-1-3-5-7/h1-6H,(H2,11,12,13,14) |
| ИнЧИКей | UDTSPKADQGPZFS-UHFFFAOYSA-N |
| SMILES | C1(=O)NC(=CC2=CC=CC=C2)C(=O)N1 |
5-БЕНЗИЛИДЕНГИДАНТОИН химические свойства, назначение, производство
Описание
Derivatives of 5-Benzylidenehydantoin are well known of their various attractive bioactivities such as anticancer, antimicrobial, antidiabetic and tyrosinase inhibitor. UPR1024 belongs to a new class of EGFR inhibitors characterized by a hydantoin nucleus and a 5-benzylidene substituent having a double bond conjugated with a carbonyl group on the hydantoin ring. The compound had antiproliferative and proapoptotic effects when tested on the non-small cell lung cancer cell line A549[1-2].5-БЕНЗИЛИДЕНГИДАНТОИН поставщик
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