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(3b,6a,12b,24R)-20,24-Epoxy-3,12,25-trihydroxydammaran-6-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside
- русский язык имя
- английское имя(3b,6a,12b,24R)-20,24-Epoxy-3,12,25-trihydroxydammaran-6-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside
- CAS №69884-00-0
- CBNumberCB5102149
- ФормулаC42H72O14
- мольный вес801.01
- номер MDLMFCD29472569
- файл Mol69884-00-0.mol
химическое свойство
Температура плавления | >196°C (dec.) |
Температура кипения | 885.3±65.0 °C(Predicted) |
плотность | 1.33±0.1 g/cm3(Predicted) |
температура хранения | 2-8°C |
растворимость | Methanol (Slightly), Pyridine (Slightly) |
пка | 12.85±0.70(Predicted) |
форма | Solid |
цвет | White |
Коды опасности | Xn | |||||||||
Заявления о рисках | 22 | |||||||||
Заявления о безопасности | 24/25 | |||||||||
WGK Германия | 3 | |||||||||
кода HS | 29389090 | |||||||||
NFPA 704: |
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рисовальное письмо(GHS)
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рисовальное письмо(GHS)
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сигнальный язык
предупреждение
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вредная бумага
H302:Вредно при проглатывании.
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оператор предупредительных мер
P301+P312+P330:ПРИ ПРОГЛАТЫВАНИИ: Обратиться за медицинской помощью при плохом самочувствии. Прополоскать рот.
(3b,6a,12b,24R)-20,24-Epoxy-3,12,25-trihydroxydammaran-6-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside химические свойства, назначение, производство
Описание
Pseudoginsenoside F11 is an ocotillol-type ginsenoside that has been found in P. ginseng and has diverse biological activities. In vivo, pseudoginsenoside F11 (10 mg/kg) prevents tubular cell apoptosis, decreases in renal glutathione peroxidase (GPX) and superoxide dismutase (SOD) levels, and increases in renal lipid peroxide levels in a rat model of nephrotoxicity induced by cisplatin . It reduces infarct size, brain water content, and cortical accumulation of autophagosomes in a rat model of ischemic stroke induced by permanent middle cerebral artery occlusion. Pseudoginsenoside F11 (4 and 8 mg/kg) inhibits morphine-induced memory impairment in the Morris water maze and development of morphine-induced conditioned place preference in mice. It also reduces hippocampal advanced glycation end product (AGE) and malondialdehyde (MDA) levels, increases hippocampal SOD activity and glutathione (GSH) levels, and attenuates cognitive impairment in the Morris water maze in a mouse model of D-galactose-induced mild cognitive impairment.Химические свойства
White solidИспользование
Pseudoginsenoside F11 is an oxotillol-type ginsenoside which displayes neuroprotective activity.(3b,6a,12b,24R)-20,24-Epoxy-3,12,25-trihydroxydammaran-6-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside поставщик
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