5- (ТЕТРАДЕЦИЛОКСИ) -2-ФУРОНОВАЯ КИСЛОТА
- английское имя5-(TETRADECYLOXY)-2-FUROIC ACID
- CAS №54857-86-2
- CBNumberCB4759746
- ФормулаC19H32O4
- мольный вес324.45
- номер MDLMFCD01726059
- файл Mol54857-86-2.mol
химическое свойство
| Температура плавления | 112-115 °C |
| Температура кипения | 441.7±25.0 °C(Predicted) |
| плотность | 1.003±0.06 g/cm3(Predicted) |
| температура хранения | -20°C |
| растворимость | DMSO: 2.5 mg/mL |
| форма | solid |
| пка | 3.55±0.10(Predicted) |
| цвет | white to beige |
| Стабильность | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month. |
| FDA UNII | BI12FRY055 |
5- (ТЕТРАДЕЦИЛОКСИ) -2-ФУРОНОВАЯ КИСЛОТА химические свойства, назначение, производство
Использование
TOFA has been used as a lipid biosynthesis inhibitor in mesenchymal stromal cells (MSCs), human pluripotent stem cells., an acetyl-CoA carboxylase 1 inhibitor in murine adipocyte cell lines., a lipolysis inhibitor in cancer stem cells (CSCs).Определение
ChEBI: A member of the class of furans that is 2-furoic acid in which the hydrogen at position 5 is replaced by a tetradecyloxy group.Биохимия/физиол Действия
5-(Tetradecyloxy)-2-furoic acid (TOFA) elicits hypolipidemic?functionality by favoring fatty acid breakdown and at the same time preventing biosynthesis. It induces apoptosis in pancreatic cancer cells and favors tumor suppression.5- (ТЕТРАДЕЦИЛОКСИ) -2-ФУРОНОВАЯ КИСЛОТА поставщик
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