8-Anilino-1-naphthalenesulfonic acid magnesium salt

Химические свойства

green crystalline powder

Общее описание

ANSA (8-Anilino-1-naphthalenesulfonic acid) is a hydrophobic polarity sensitive fluorescent dye useful as a site probe to detect conformational changes in cell and micelle membranes and molecules such as proteins. ANSA is also used as a fluorescent probe for the estimation of the critical micelle concentration (CMC) of surfactants.

Свойства и приложения

GV et al. researched the luminescence of 8-anilino-1-naphthalenesulfonic acid magnesium salt as a hydrophobic probe, which was investigated under the conditions of three-dimensional radical polymerization of methacrylic macromonomers of poly(ethylene oxide) in an aqueous medium. They found that the luminescence intensity rises in the course of gel formation, which is caused by the binding of the probe to hydrophobic polyfunctional branching nodes formed upon the polymerization of terminal methacrylic groups of the macromonomer. Interaction of 8-aniline-1-naphthalenesulfonic acid with a swelled PEO hydrogel also leads to a growth of the luminescence intensity as compared to that in the solution of macromonomers. The addition of NaCl enhances the emission of 8-anilino-1-naphthalenesulfonic acid, probably due to the densification of hydrophobic regions and an increase in the energy of probe binding in these regions[1].