6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine
- русский язык имя
- английское имя6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine
- CAS №873436-91-0
- CBNumberCB42554288
- ФормулаC18H21IN6O2S
- мольный вес512.37
- номер MDLMFCD28952784
- файл Mol873436-91-0.mol
химическое свойство
| Температура плавления | >194oC (dec.) |
| Температура кипения | 650.6±65.0 °C(Predicted) |
| плотность | 1.84 |
| температура хранения | under inert gas (nitrogen or Argon) at 2–8 °C |
| растворимость | DMSO (Slightly), Methanol (Slightly) |
| пка | 10.16±0.29(Predicted) |
| форма | Solid |
| цвет | Off-White to Pale Beige |
| FDA UNII | 06IVK87M04 |
6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine химические свойства, назначение, производство
Использование
Trifluoroacetic Acid of PU-H71 is a potent Hsp90 inhibitor (IC50 = 50 nM). Hsp90 plays a critical role in modulating the activity of many cell signaling proteins and are an attractive target for anti-cancer therapeutics. Studies indicate that Hsp90 inhibitors may serve as potential anti-Parkinson′s disease.6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine поставщик
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