ANTI-MTBP (IN2)
- русский язык имя
- английское имяANTI-MTBP (IN2)
- CAS №
- CBNumberCB3432585
- мольный вес0
- номер MDLMFCD03097063
- файл MolMol file
ANTI-MTBP (IN2) химические свойства, назначение, производство
Биохимия/физиол Действия
The gene MTBP (Mdm2-binding protein) is mapped to human chromosome 8q24. It is involved in the development and progression of cancer. In hepatocellular carcinoma, MTBP enhances MDM2 (E3 ubiquitin-protein ligase)-associated degradation of E-cadherin. It is also suggested as a therapeutic target for treatment of triple-negative breast cancer. MTBP is a transcriptional target of Myc. It plays an important role in cell cycle progression. Silencing of this gene causes delay in cell cycle progress at S and G2/M phases.