ANTI-MOUSE IGG (GAMMA-CHAIN SPECIFIC)-ALKALINE PHOSPHATASE

Использование

Goat anti-mouse IgG (gamma-chain specific)-alkaline phosphatase antibodies can be used for western blot assays,.

Общее описание

Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases . Mouse IgGs have four distinct isotypes, namely, IgG1, IgG2a, IgG2b, and IgG3. IgG1 regulates complement fixation in mice . Anti-Mouse IgG (γ-chain specific)-Alkaline Phosphatase antibody is specific for mouse IgG when tested against purified mouse IgA, IgG and IgM myeloma proteins.

Биохимия/физиол Действия

Digestion of IgG by papain results in generation of fragment antigen binding (Fab) comprising of one complete L chain and a variable and CH1 region of H chain. Pepsin digestion of IgG results in fragment crystallizable (fc), comprises of the H chain constant region. IgG is abundant immunoglobulin in proteins in human serum. The four classes of IgG can be IgG1, IgG2, IgG3, and IgG4. IgG antibody has enormous therapeutic potential and the Fc are is for the development of therapeutic antibody.