CHONDROITIN SULFATE B SODIUM SALT

Химические свойства

Also available: fractionated dermatan sulfates with Av. Mw 25,000 ± 2,500 and 50,000 ± 5,000 and different Anti-Xa and Anti-IIa activities. Please inquire

Использование

Antithrombotic.

Общее описание

Chondroitin, a glucosaminoglycan (GAG), is a polysaccharide chain of alternating units of N-acetylgalactosamine (GalNAc) and glucuronic acid (GlcA) that can be sulfated on the either or both GalNAc and GlcA units. Chondroitin and its sulfates are frequently attached to proteins to form proteoglycans. Chondroitin sulfate B (Dermatam sulfate) is a component of proteoglycans such as decorin, biglycan and versican. Chondroitin sulfate B is used to study β peptide (1-42) cytotoxicity.

Методы очистки

Dermatan sulfate is purified by digestion with papain and hyaluronidase, and fractionation using aqueous EtOH. [Gifonelli & Roden Biochemical Preparations 12 1 1968.]