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Ибутаморен
- английское имяMK-677
- CAS №159634-47-6
- CBNumberCB31178916
- ФормулаC27H36N4O5S
- мольный вес528.66
- EINECS231-830-3
- номер MDLMFCD00867473
- файл Mol159634-47-6.mol
химическое свойство
плотность | 1.32 |
пка | 15.73±0.46(Predicted) |
ИнЧИКей | UMUPQWIGCOZEOY-JOCHJYFZSA-N |
SMILES | C(N[C@H](COCC1=CC=CC=C1)C(N1CCC2(CC1)C1=C(N(S(C)(=O)=O)C2)C=CC=C1)=O)(=O)C(N)(C)C |
FDA UNII | GJ0EGN38UL |
рисовальное письмо(GHS)
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рисовальное письмо(GHS)
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сигнальный язык
опасность
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вредная бумага
H301:Токсично при проглатывании.
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оператор предупредительных мер
P264:После работы тщательно вымыть кожу.
P270:При использовании продукции не курить, не пить, не принимать пищу.
P301+P310:ПРИ ПРОГЛАТЫВАНИИ: Немедленно обратиться за медицинской помощью. Прополоскать рот.
P405:Хранить в недоступном для посторонних месте.
P501:Удалить содержимое/ контейнер на утвержденных станциях утилизации отходов.
Ибутаморен химические свойства, назначение, производство
Описание
Ibutamoren (INN) (developmental code names MK-677, MK-0677, L-163,191)is a non-peptidic, potent, long acting, orally-active, and selective agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin.It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including GH and insulin-like growth factor 1 (IGF-1), but without affecting cortisol levels. MK677 has shown to sustain activation of GH-IGF-1 Axis and increase in lean body mass but no change in total fat mass or visceral fat.
It is currently under development as a potential treatment for reduced levels of these hormones, such as in children or elderly adults with growth hormone deficiency, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly.
Использование
Growth hormone releasing factor.преимущество
The benefits of MK-677 include muscle-building, a reduction in muscle wasting, better bone density, improved sleep, and anti-aging properties. It may also have nootropic effects and it can be beneficial in treating growth hormone deficiencies.Безопасность
Ibutamoren is a muscle building anabolic compound. It's considered safe if you don't have high blood glucose level and if you don't suffer from congestive heart failure. It's considered a boon for anti aging and it's a life longevity material. It's considered to be more beneficial than to be harmful. The optimal dose for body building is to take 25mg at bedtime for four to six weeks. It is a water retaining compound so beware of bloating.Ибутаморен запасные части и сырье
сырьё
- Spiro[3H-indole-3,4'-piperidine], 1'-[(2R)-2-amino-1-oxo-3-(phenylmethoxy)propyl]-1,2-dihydro-1-(methylsulfonyl)-
- Spiro[3H-indole-3,4'-piperidine]-1'-carboxylic acid, 1,2-dihydro-1-(methylsulfonyl)-, phenylmethyl ester
- (R)-tert-butyl (3-(benzyloxy)-1-(1-(methylsulfonyl)spiro[indoline-3,4'-piperidin]-1'-yl)-1-oxopropan-2-yl)carbamate
- Бензил-4-(хлоркарбонил)тетрагидро-1(2H)-пиридинкарбоксилат
- 1-(метилсульфонил)спиро[индолин-3,4'-пиперидин]
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Ибутаморен поставщик
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