(+/-)-BAY K 8644
- русский язык имя
- английское имя(+/-)-BAY K 8644
- CAS №93468-89-4
- CBNumberCB2471785
- ФормулаC16H15F3N2O4
- мольный вес356.3
- номер MDLMFCD00036697
- файл Mol93468-89-4.mol
химическое свойство
Температура плавления | 166-172 °C |
температура хранения | 2-8°C |
растворимость | DMSO: 184 mg/mL |
форма | Yellow solid |
(+/-)-BAY K 8644 химические свойства, назначение, производство
Общее описание
Synthetic dihydropyridine derivative that acts as an active Ca2+ slow channel agonist in neuroendocrine, muscle, thyroid and other cell types. Prolongs single channel open time without affecting the close time. An L-type Ca2+ channel agonist. Composed of two optical isomers. The (-)-enantiomer has strong vasoconstrictive, positive inotropic, and Ca2+ agonistic properties, whereas the (+)-enantiomer has weakly vasodilating, negative inotropic, and Ca2+ antagonistic properties. The net effect of the racemic mix is that of the negative enantiomer. Promotes β-cell proliferation/regeneration.Биохимия/физиол Действия
Primary TargetL-type Ca2+ channel(+/-)-BAY K 8644 поставщик
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