4'-ХЛОР-3-МЕТОКЦИЦИНМАНИЛИД
- английское имя4'-CHLORO-3-METHOXYCINNAMANILIDE
- CAS №472981-92-3
- CBNumberCB2449409
- ФормулаC16H14ClNO2
- мольный вес287.74
- номер MDLMFCD01033818
- файл Mol472981-92-3.mol
химическое свойство
| Температура плавления | 165-167℃ |
| температура хранения | Sealed in dry,Room Temperature |
| растворимость | DMSO: 13 mg/mL, soluble |
| форма | solid |
| цвет | off-white |
| Стабильность | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| FDA UNII | E8EY4M2N4H |
| Заявления о безопасности | 22-24/25 |
| WGK Германия | 3 |
| кода HS | 2924.29.7790 |
4'-ХЛОР-3-МЕТОКЦИЦИНМАНИЛИД химические свойства, назначение, производство
Использование
N-(4-Methoxyphenyl)-4-chlorocinnamamide is a novel, potent, and selective cinnamide TRPV1 antagonist. Also a useful tool to further study the biology of TRPV1.Биологическая активность
Potent, selective and competitive vanilloid TRPV1 (VR1) receptor antagonist (pA 2 = 7.71 at hVR1); antagonizes hTRPV1 receptors activated by agonists, noxious heat, but not protons. Displays selectivity over a wide range of receptors and systems including CB 1 and CB 2 receptors, voltage-gated Ca 2+ channels and the hyperpolarization-activated current (I h ). Also available as part of the Vanilloid TRPV1 Receptor Tocriset™ .Биохимия/физиол Действия
SB-366791 might exhibit analgesic properties on bone cancer-related pain behavior.4'-ХЛОР-3-МЕТОКЦИЦИНМАНИЛИД поставщик
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