(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide
- русский язык имя
- английское имя(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide
- CAS №1417997-93-3
- CBNumberCB23373154
- ФормулаC22H19NO3
- мольный вес345.39
- EINECS-0
- номер MDLMFCD31619280
- файл Mol1417997-93-3.mol
химическое свойство
| плотность | 1?+-.0.06 g/cm3(Predicted) |
| температура хранения | Store at -20°C |
| растворимость | DMSO: soluble |
| форма | A solid |
| пка | 8.76±0.23(Predicted) |
| цвет | White to off-white |
| UNSPSC Code | 12352200 |
(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide химические свойства, назначение, производство
Описание
HDAC8-IN-1 is an inhibitor of histone deacetylase 8 (HDAC8; IC50 = 27.2 nM). It is selective for HDAC8 over HDAC1-3, -4, -6, -10, and -11 (IC50s = ≥3,000 nM for all). HDAC8-IN-1 is cytotoxic to A549, H1299, and CL1-5 lung cancer cells (IC50s = 7.9, 7.2, and 7 μM, respectively).Использование
(2E)-N-Hydroxy-3-(5-methoxy[1,1'':4'',1''''-terphenyl]-2-yl)-2-propenamide, is a HDAC8 inhibitor with an IC50 of 27.2 nM.(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide запасные части и сырье
(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide поставщик
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