Glucagon Receptor Antagonist I
- русский язык имя
- английское имяGlucagon Receptor Antagonist I
- CAS №438618-32-7
- CBNumberCB23136786
- ФормулаC20H30N2OS
- мольный вес346.53
- номер MDLMFCD01920208
- файл Mol438618-32-7.mol
химическое свойство
| Температура кипения | 517.8±50.0 °C(Predicted) |
| плотность | 1.07±0.1 g/cm3(Predicted) |
| температура хранения | Store at -20°C |
| растворимость | DMSO: soluble |
| форма | White crystalline solid. |
| пка | 13.46±0.40(Predicted) |
Glucagon Receptor Antagonist I химические свойства, назначение, производство
Описание
Glucagon receptor antagonist I is a competitive antagonist of the glucagon receptor (GCGR; IC50 = 181 nM). It blocks glucagon-induced glycogenolysis in primary human hepatocytes and isolated liver. Glucagon receptor antagonist I, at 50 mg/kg, reduces the increase in glucose levels observed after intraperitoneal administration of glucagon in humanized mice. Glucagon receptor antagonist inactive control does not prevent glucagon-mediated actions.Glucagon Receptor Antagonist I поставщик
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