P7C3-A20
- русский язык имя
- английское имяP7C3-A20
- CAS №1235481-90-9
- CBNumberCB22686079
- ФормулаC22H19Br2FN2O
- мольный вес506.21
- EINECS-0
- номер MDLMFCD28023591
- файл Mol1235481-90-9.mol
химическое свойство
| Температура кипения | 641.3±55.0 °C(Predicted) |
| плотность | 1.57±0.1 g/cm3(Predicted) |
| температура хранения | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| растворимость | Soluble in DMSO (40 mg/ml) |
| пка | 3.25±0.50(Predicted) |
| форма | solid |
| цвет | Off-white |
| Стабильность | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
P7C3-A20 химические свойства, назначение, производство
Описание
P7C3-A20 is a derivative of P7C3 (Item No. 16682) that has proneurogenic and neuroprotective activity. It increases proliferation in the subgranular zone (SGZ) of the adult mouse dentate gyrus in a dose-dependent manner when administered at doses ranging from 0.1 to 10 μM. It also protects U2OS cells from calcium-induced mitochondrial dissolution. In a rat model of traumatic brain injury, P7C3-A20 (10 mg/kg, i.p., twice daily for one week) decreases contusion volume, increases proliferation in the SGZ, and decreases the latency to reach the platform in the Morris water maze to sham surgery control levels. It also prevents or reverses dopaminergic cell death and motor deficits in a 6-OHDA rat model of Parkinson's disease.P7C3-A20 запасные части и сырье
P7C3-A20 поставщик
| поставщик | телефон | страна | номенклатура продукции | благоприятные условия |
|---|---|---|---|---|
| +undefined-27-86652399 +undefined13627115097 |
China | 942 | 58 | |
| +undefined-21-51877795 | China | 32965 | 60 | |
| +86-0371-86658258 +8613203830695 |
China | 29871 | 58 | |
| 0086-13720134139 | CHINA | 965 | 58 | |
| +1-631-485-4226 | United States | 19553 | 58 | |
| +86-021-61551413 +8618813727289 |
China | 5738 | 58 | |
| +1-781-999-5354 +1-00000000000 |
United States | 32161 | 58 | |
| +8617786394783 | China | 300 | 58 | |
| +1-2135480471 +1-2135480471 |
China | 10473 | 58 | |
| +86-0571-81612335 +8613336028439 |
China | 19908 | 58 |