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Воск микрокристаллический
- английское имяMICROCRYSTALLINE WAX
- CAS №63231-60-7
- CBNumberCB2265898
- Формулаunspecified
- мольный вес0
- EINECS264-038-1
- номер MDLMFCD00675940
- файл MolMol file
химическое свойство
растворимость | Soluble in benzene, chloroform, and ether; slightly soluble in ethanol; practically insoluble in water. When melted, microcrystalline wax is miscible with volatile oils and most warm fixed oils. |
Запах | at 100.00?%. odorless |
FDA UNII | XOF597Q3KY |
Система регистрации веществ EPA | Microcrystalline paraffin waxes and hydrocarbon waxes (63231-60-7) |
Воск микрокристаллический химические свойства, назначение, производство
Химические свойства
Microcrystalline wax occurs as odorless and tasteless waxy lumps or flakes containing small irregularly shaped crystals. It may vary in color from white to yellow, amber, brown, or black depending on the grade of material; pharmaceutical grades are usually white or yellow.The USP32–NF27 describes microcrystalline wax as a mixture of straight-chain, branched-chain, and cyclic hydrocarbons, obtained by solvent fractionation of the still-bottom fraction of petroleum by suitable means of dewaxing or de-oiling.
Методы производства
Microcrystalline wax is obtained by solvent fractionation of the still-bottom fraction of petroleum by suitable dewaxing or deoiling.Фармацевтические приложения
Microcrystalline wax is used mainly as a stiffening agent in topical creams and ointments.The wax is used to modify the crystal structure of other waxes (particularly paraffin wax) present in a mixture so that changes in crystal structure, usually exhibited over a period of time, do not occur. Microcrystalline wax also minimizes the sweating or bleeding of oils from blends of oils and waxes. Microcrystalline wax generally has a higher melting point than paraffin wax, and higher viscosity when molten, thereby increasing the consistency of creams and ointments when incorporated into such formulations.
Microcrystalline wax is also used in oral controlled-release matrix pellet formulations for various active compounds and as a tablet- and capsule-coating agent. In controlled-release systems, microcrystalline wax coatings can also be used to affect the release of drug from ion-exchange resin beads.
Microcrystalline wax is also used in confectionery, cosmetics, and food products.
Безопасность
Microcrystalline wax is mainly used in topical pharmaceutical formulations but is also used in some oral products. It is generally regarded as a nontoxic and nonirritating material.хранилище
Microcrystalline wax is stable in the presence of acids, alkalis, light, and air. The bulk material should be stored in a well-closed container in a cool, dry place.Регуляторный статус
GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (oral capsules; topical and vaginal preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.Воск микрокристаллический запасные части и сырье
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Воск микрокристаллический поставщик
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