Основные атрибуты  химическое свойство Информация о безопасности химические свойства, назначение, производство MSDS запасные части и сырье поставщик Обзор
Тартразин структурированное изображение

Тартразин

  • английское имяTartrazine
  • CAS №1934-21-0
  • CBNumberCB2219301
  • ФормулаC16H13N4NaO9S2
  • мольный вес492.41
  • EINECS217-699-5
  • номер MDLMFCD00148908
  • файл Mol1934-21-0.mol
химическое свойство
Температура плавления 300 °C
Температура кипения 909.54℃[at 101 325 Pa]
плотность 2.121[at 20℃]
давление пара 0Pa at 25℃
температура хранения room temp
растворимость DMSO (Sparingly, Heated), Water (Slightly)
Цветовой индекс 19140
форма Powder
цвет Orange
Растворимость в воде 260 g/L (30 ºC)
Чувствительный Hygroscopic
Мерк 14,9072
БРН 69850
Стабильность Stable. Hygroscopic. Incompatible with strong oxidizing agents.
Биологические приложения Treating hepatitis,periodontal disease,psoriasis
LogP -1.572 at 20℃
FDA 21 CFR 74.1705; 74.2705; 74.705; 82.705
Вещества, добавляемые в пищу (ранее EAFUS) FD&C YELLOW NO. 5
Рейтинг продуктов питания EWG 2-5
FDA UNII I753WB2F1M
Система регистрации веществ EPA Tartrazine (1934-21-0)
UNSPSC Code 85151701
NACRES NA.47
больше
Заявления об опасности и безопасности
Коды опасности Xn
Заявления о рисках 42/43
Заявления о безопасности 22-36/37-45-24/25
WGK Германия 1
RTECS UQ6400000
TSCA Yes
кода HS 32129000
Банк данных об опасных веществах 1934-21-0(Hazardous Substances Data)
Токсичность LD50 oral in mouse: 12750mg/kg
NFPA 704:
1
1 0

рисовальное письмо(GHS)

  • рисовальное письмо(GHS)

    GHS hazard pictograms

  • сигнальный язык

    опасность

  • вредная бумага

    H317:При контакте с кожей может вызывать аллергическую реакцию.

    H334:При вдыхании может вызывать аллергическую реакцию (астму или затрудненное дыхание).

  • оператор предупредительных мер

    P261:Избегать вдыхания пыли/ дыма/ газа/ тумана/ паров/ аэрозолей.

    P272:Не уносить загрязненную спецодежду с места работы.

    P280:Использовать перчатки/ средства защиты глаз/ лица.

    P284:Использовать средства защиты органовдыхания.

    P304+P340:ПРИ ВДЫХАНИИ: Свежий воздух, покой.

    P501:Удалить содержимое/ контейнер на утвержденных станциях утилизации отходов.

Тартразин MSDS

Тартразин химические свойства, назначение, производство

Описание

FD & C Yellow No. 5 is principally the trisodium salt of 4,5-dihydro-5-oxo-l-(4-sulfophenyl)-4-[4-sulfophenyl-azo]-lH- pyrazole-3-carboxylic acid.
The colorant is a yellow-orange powder that dissolves in water to give a solution golden yellow at neutrality and in acid. When dissolved in concentrated sulfuric acid, it yields an orange-yellow solution that turns yellow when diluted with water.
FD & C Yellow No. 5 is regularly used in desserts (e.g., dessert powders, puddings, custards, gelatin, ice cream), candy, preserves, beverages (including carbonated soda beverages and flavored drink powders), prepared meats, and canned and frozen vegetables. It is also used in pharmaceuticals and cosmetics.1 .

Химические свойства

Deep yellow powder

Использование

Tartrazine is used as a dye for wool and silks; as colorant in food, drugs, and cosmetics. In biochemistry as an adsorption-elution indicator for chloride estimations. Tartrazine (otherwise known as E number E102, C.I. 19140, or FD&C Yellow 5) is a synthetic lemon yellow azo dye used as a food coloring. Tartrazine appears to cause the most allergic and intolerance reactions of all the azo dyes, particularly among as thmatics and those with an aspirin intolerance.

Подготовка

Commonly known??Tartmzine ?. (a) 4-Aminobenzenesulfonic acid diazo, and 5-Oxo-1-(4-sulfophenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid coupled; (b) 2 Moore 4-Aminobenzenesulfonic acid?and dioxide 5 diacid reaction

Определение

ChEBI: An organic sodium salt which is the trisodium salt of tartrazine acid. A synthetic lemon yellow azo dye used as a food colouring.

Всемирная организация здравоохранения(ВОЗ)

Tartrazine is widely used as a permitted colouring agent in food and pharmaceutical preparations. Its use has been associated with allergic reactions some of which have been severe. Several national drug regulatory authorities now require a warning on labels of products containing tartrazine and some manufacturers have voluntarily withdrawn this compound from their products.

Общее описание

Tartrazine is a synthetic azo dye, commonly found in drugs, food products and cosmetics. It can be synthesized by the reaction of sulfanilic acid with 3-carboxy-l-(4-sulfophenyl)-5-pyrazolone.

Опасность

An allergen.

Профиль безопасности

Low toxicity by ingestion. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx, SOx, and Na2O.

Токсикология

This coloring agent is 5-hydroxy-1-p-sulfophenyl-4-(p-sulfophenylazo)- pyrazol-3-carboxylic acid, trisodium salt. It is a yellow powder and has been used as food coloring additive since 1916. Tartrazine is known as the least toxic coloring agent among synthetic coloring chemicals. The median acute oral lethal dose of tartrazine in mice is 12.17 g/kg. Beagle dogs received tartrazine as 2% of the diet for two years without adverse effects, with the possible exception of pyloric gastritis in one dog. Tumor incidence was unchanged relative to controls, in rats receiving tartrazine at 1.5% of the diet for 64 weeks, and in rats administered this dye at 5.0% of the diet for two years.
Human sensitivity to tartrazine has been reported with some frequency and has been estimated to occur in 1/10,000 persons. Anaphylactic shock, potentially life-threatening, has been reported but symptoms more commonly cited are urticaria (hives), asthma, and purpura (blue or purple spots on the skin or mucous membrane).

Тартразин поставщик

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