CYP3cide
- русский язык имя
- английское имяCYP3cide
- CAS №1390637-82-7
- CBNumberCB12620906
- ФормулаC26H32N8
- мольный вес456.59
- номер MDLMFCD22417344
- файл Mol1390637-82-7.mol
химическое свойство
| Температура кипения | 630.2±55.0 °C(Predicted) |
| плотность | 1.34±0.1 g/cm3(Predicted) |
| температура хранения | room temp |
| растворимость | Soluble in DMSO |
| форма | powder |
| пка | 8.88±0.20(Predicted) |
| цвет | white to beige |
| FDA UNII | ZRD2TT3Y1T |
| UNSPSC Code | 12161501 |
| NACRES | NA.77 |
CYP3cide химические свойства, назначение, производство
Химические свойства
White to Off-White SolidИспользование
CYP3cide is a potent and selective time dependent inactivator of Cytochrome P450 3A4 (CYP3A4). CYP3A4 is an important enzymes involved in the metabolism of xenobiotics in the human body and constitutes to about a quarter of all CYPs in the human body. CYP3cide provides a useful in vitro tool in defining the individual roles of CYP3A4 versus CYP3A5 in the metabolism of drugs.Биохимия/физиол Действия
CYP3cide is a mechanism-based inhibitor of cytochrome P4503A4 that can be used to distinguish the contributions of CYP3A4 versus CYP3A5 on drug metabolism. The IC50 values for inhibition of Midazolam 1′-Hydroxylase activity of recombinant CYP3A4 and CYP3A5 by CYP3cide are 0.3 and 17 mM, respectively.CYP3cide поставщик
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