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RIBOSTAMYCIN SULFATE SALT
- русский язык имя
- английское имяRIBOSTAMYCIN SULFATE SALT
- CAS №25546-65-0
- CBNumberCB1165751
- ФормулаC17H34N4O10
- мольный вес454.47
- EINECS247-091-5
- номер MDLMFCD00057496
- файл Mol25546-65-0.mol
химическое свойство
Температура плавления | 192-195°; mp 175-180° (dec) |
альфа | D23 +42° |
Температура кипения | 561.28°C (rough estimate) |
плотность | 1.1751 (rough estimate) |
показатель преломления | 1.6700 (estimate) |
температура хранения | 2-8°C |
пка | 7.70(at 25℃) |
FDA UNII | 2Q5JOU7T53 |
Код УВД | J01GB10 |
Коды опасности | T |
Заявления о рисках | 61-20/21/22 |
Заявления о безопасности | 53-22-36/37/39-45 |
WGK Германия | 3 |
RTECS | WK2300000 |
Токсичность | mouse,LD50,intracrebral,66800ug/kg (66.8mg/kg),BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLDLUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION,Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 2489, 1970. |
RIBOSTAMYCIN SULFATE SALT химические свойства, назначение, производство
Описание
Ribostamycin was found in the culture broth of Streptomyces ribosidificus by Meiji Seika Kaisha in 1970 in the course of screening aminoglycoside antibiotics. It is structurally related to neomycin but lacks the diaminoidose (glucose) moiety substituted on the ribose moiety. Ribostamycin is much less toxic than neomycin and shows strong activity against a variety of gram-positive and gram-negative bacteria, except Pseudomonas aeruginosa. It is used parenterally for therapy of urinary tract, respiratory tract, surgical, and other infections.Определение
ChEBI: An amino cyclitol glycoside that is 4,6-diaminocyclohexane-1,2,3-triol having a 2,6-diamino-2,6-dideoxy-alpha-D-glucosyl residue attached at position 1 and a beta-D-ribosyl residue attache at position 2. It is an antibiotic produced by Streptomyces ribosidificus (formerly S. thermoflavus).RIBOSTAMYCIN SULFATE SALT поставщик
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