Ergoline-8-methanol, 10-hydroxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8β)-
- русский язык имя
- английское имяErgoline-8-methanol, 10-hydroxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8β)-
- CAS №57935-66-7
- CBNumberCB08366638
- ФормулаC23H24BrN3O3
- мольный вес470.37
- файл Mol57935-66-7.mol
химическое свойство
Температура кипения | 621.7±55.0 °C(Predicted) |
плотность | 1.54±0.1 g/cm3(Predicted) |
пка | 13.80±0.40(Predicted) |
Ergoline-8-methanol, 10-hydroxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8β)- химические свойства, назначение, производство
Использование
10α-Hydroxy Nicergoline is an impurity of Nicergoline (N394550) which is a drug used for age-dependent cognitive impairment such as Alzheimers disease and other types of dementia. Nicergoline has shown to protect cultured neurons against β-amyloid toxicity. Nicergoline protects against neuronal cell death induced by activated microglia and astrocytes through the inhibition of inflammatory mediators and the upregulation of neurotrophic factors by glial cells. Nicergoline is a drug used for age-dependent cognitive impairment and it protects cultured neurons against β-amyloid toxicity.Ergoline-8-methanol, 10-hydroxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8β)- поставщик
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