Основные атрибуты  химическое свойство Информация о безопасности химические свойства, назначение, производство запасные части и сырье поставщик Обзор
 структурированное изображение

Huperzine A

  • русский язык имя
  • английское имяHuperzine A
  • CAS №120786-18-7
  • CBNumberCB0308078
  • ФормулаC15H18N2O
  • мольный вес242.32
  • EINECS200-001-8
  • номер MDLMFCD00171439
  • файл Mol120786-18-7.mol
химическое свойство
Температура кипения 505.0±50.0 °C(Predicted)
плотность 1.20±0.1 g/cm3(Predicted)
температура хранения 2-8°C
растворимость DMSO : ≥ 50 mg/mL (206.34 mM)
пка 12.25±0.60(Predicted)
форма solid
цвет White or off-white
InChI InChI=1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/b11-3+
ИнЧИКей ZRJBHWIHUMBLCN-QDEBKDIKSA-N
SMILES C12CC3/C(=C\C)/C(N)(C=1C=CC(=O)N2)CC(C)=C3
Справочник по базе данных CAS 120786-18-7
FDA UNII 0111871I23
Заявления об опасности и безопасности
Коды опасности T
Заявления о рисках 23/24/25-36/37/38
Заявления о безопасности 26-36/37/39-45
РИДАДР UN 1544 6.1/PG 2
WGK Германия 3
RTECS PB9185700

рисовальное письмо(GHS)

  • рисовальное письмо(GHS)

    GHS hazard pictograms

  • сигнальный язык

    опасность

  • вредная бумага

    H315:При попадании на кожу вызывает раздражение.

    H319:При попадании в глаза вызывает выраженное раздражение.

    H335:Может вызывать раздражение верхних дыхательных путей.

    H301+H311+H331:Токсично при проглатывании, при контакте с кожей или при вдыхании.

  • оператор предупредительных мер

    P261:Избегать вдыхания пыли/ дыма/ газа/ тумана/ паров/ аэрозолей.

    P280:Использовать перчатки/ средства защиты глаз/ лица.

    P301+P310:ПРИ ПРОГЛАТЫВАНИИ: Немедленно обратиться за медицинской помощью. Прополоскать рот.

    P302+P352+P312:ПРИ ПОПАДАНИИ НА КОЖУ: Промыть большим количеством воды. Обратиться за медицинской помощью при плохом самочувствии.

    P304+P340+P311:ПРИ ВДЫХАНИИ: Свежий воздух, покой. Обратиться за медицинской помощью.

    P305+P351+P338:ПРИ ПОПАДАНИИ В ГЛАЗА: Осторожно промыть глаза водой в течение нескольких минут. Снять контактные линзы, если Вы ими пользуетесь и если это легко сделать. Продолжить промывание глаз.

Huperzine A химические свойства, назначение, производство

Описание

Huperzine A is an alkaloid extract derived from the Chinese club moss Huperzia serrata. It is an acetylcholinesterase inhibitor. This means it helps promote higher levels of acetylcholine in the brain. Higher levels of acetylcholine support ones ability to perform cognitive tasks such as learning new things, memorizing information, and focusing at the task at hand. Huperzine A is considered to be a nootropic supplement because it supports cognitive function. It is considered a focus and memory nootropic similar to alpha gpc, bacopa, phosphatidylcholine, cdp choline, sulbutiamine, and uridine. It is also considered a brain booster as it is used for brain health and support.
Huperzine A for many years has been widely used in traditional Chinese medicine to enhance memory and to treat fever and inflammation. In the United States it is commercially available as a food supplement, but has not been approved by the FDA as a treatment for AD or other cognition disorders.

Вхождение

The herbs of Lycopodium serratum.

Использование

Huperzine A is used for dementia in Alzheimer's disease and for muscle weakness in myasthenia gravis. In Alzheimer's disease, Huperzine A leads to significant improvements in memory and cognitive and behavioral function.

прикладной

(+/-)-Huperzine A is an NMDA antagonist. It has been used in anti-acetylcholinesterase bioautographic assay.

преимущество

Huperzine A can help support learning and memory by protecting acetylcholine, a neurotransmitter that acts as a messenger molecule in the brain. Huperzine A may be used for both short-term "brain boost" needs, such as preparing for a test, as well as more long-term needs, such as reducing the mild memory loss associated with normal aging.
ACETYLCHOLINESTERASE INHIBITOR - Huperzine A acts as a reversible Acetylcholinesterase inhibitor meaning it supports levels of the neurotransmitter acetylcholine which plays a key role in cognitive function.
SUPPORTS COGNITIVE FUNCTION - Supports working memory, motivation, and problem solving ability.
SUPPORTS ENERGY AND STAMINA - Huperzine A supports mental energy, stamina, and sustained focus.

Биологическая активность

Huperzine A is an effective acetylcholinesterase inhibitor and can cross the blood-brain barrier. Huperzine A is known to prevent cognitive defects, glutamate-induced nerve cell death.It is recognized for its use in the treatment of Alzheimer′s disease and organophosphate poisoning.

Побочные эффекты

When taken at recommended doses Huperzine A is well tolerated and presents few side effects. Rarely, side effects including nausea, diarrhea, and loss of appetite may occur. Adverse side effects are more likely when exceeding the recommended dosage.
Huperzine A is not recommended for people suffering from heart conditions, consult your physician before taking this product.

Способ действия

Huperzine A is a reversible acetycholinesterase inhibitor that can cross the blood-brain barrier. This constituent can inhibit the activity of acetycholinesterase in the brain for several hours, which allows for increased levels of acetylcholine in different areas of the brain. Because of its effects on acetylcholine, Huperzine A is considered a beneficial therapuetic agent in the treatment of memory impairment, myasthenia gravis, and dementia.
Herbs and Nutrients for the Mind A Guide to Natural Brain Enhancers By Chris D. Meletis, Jason E. Barker · 2004

Huperzine A поставщик

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