PERUVOSIDE
- русский язык имя
- английское имяPERUVOSIDE
- CAS №1182-87-2
- CBNumberCB0266619
- ФормулаC30H44O9
- мольный вес548.66
- EINECS214-659-9
- номер MDLMFCD00133752
- файл Mol1182-87-2.mol
химическое свойство
| Температура плавления | 161-164°C |
| альфа | D22 -71.7° (c = 1.54 in methanol) |
| Температура кипения | 540.83°C (rough estimate) |
| плотность | 1.1277 (rough estimate) |
| показатель преломления | 1.5500 (estimate) |
| температура хранения | 2-8°C |
| растворимость | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| пка | 12.92±0.70(Predicted) |
| форма | powder |
| цвет | light yellow |
| FDA UNII | CT36KGC6A6 |
| Код УВД | C01AX02 |
| Коды опасности | T |
| Заявления о рисках | 23/24/25 |
| Заявления о безопасности | 36/37/39-45 |
| WGK Германия | 3 |
| RTECS | FH4915000 |
| Токсичность | cat,LD50,intravenous,145ug/kg (0.145mg/kg),GASTROINTESTINAL: NAUSEA OR VOMITINGCARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)CARDIAC: CHANGE IN RATE,Archives Internationales de Pharmacodynamie et de Therapie. Vol. 126, Pg. 412, 1960. |
PERUVOSIDE химические свойства, назначение, производство
Использование
Peruvoside is a cardiac glycoside with the same inotropic and chronotropic effects on heart function as Ouabain (O714500).Ферментативный ингибитор
This cardiotonic glycoside or cardenoide (FW = 548.67 g/mol; CAS 1182- 87-2), named systematically as (3b,5b)-3-(6-deoxy-3-O-methyl-a-Lglucopyranosyl)oxyl-14-hydroxy-19-oxocard-20(22)-enolide, a component of neriperside from Thevetia neriifolia (yellow oleander) resembles oubain in its inotropic (force of contraction) and chronotropic (rate of contraction) effects on heart function. Orally administered peruvoside is effective in treating congestive heart failure. Note the structural similarities of the aglycon to digitoxigenin. Target(s): Na+ /K+ -exchanging ATPase.PERUVOSIDE поставщик
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