N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
- русский язык имя
- английское имяN-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
- CAS №289472-81-7
- CBNumberCB02661665
- ФормулаC19H24N4O3
- мольный вес356.42
- файл Mol289472-81-7.mol
химическое свойство
Температура кипения | 672.0±55.0 °C(Predicted) |
плотность | 1.199±0.06 g/cm3(Predicted) |
температура хранения | 2-8°C |
растворимость | Chloroform (Slightly), Methanol (Slightly) |
пка | 11.90±0.46(Predicted) |
форма | Solid |
цвет | White to Off-White |
FDA UNII | BGP3WC2T3P |
N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide химические свойства, назначение, производство
Использование
(S)-Hydroxy Des(boric Acid) Bortezomib is an impurity in the synthesis of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide поставщик
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