1-(5-O-Phosphono-2,3-dideoxy-β-D-glycero-penta-2-enofuranosyl)-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
- русский язык имя
- английское имя1-(5-O-Phosphono-2,3-dideoxy-β-D-glycero-penta-2-enofuranosyl)-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
- CAS №3715-64-8
- CBNumberCB02307945
- ФормулаC10H15N2O7P
- мольный вес306.21
- файл Mol3715-64-8.mol
химическое свойство
| плотность | 1.547±0.06 g/cm3(Predicted) |
| пка | 1.86±0.10(Predicted) |
| FDA UNII | R6VJB6HJ6Y |
1-(5-O-Phosphono-2,3-dideoxy-β-D-glycero-penta-2-enofuranosyl)-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione химические свойства, назначение, производство
Использование
3`-Deoxy-5`-thymidylic Acid has been shown to complex with human thymidylate kinase via hydrogen bonding between Arg97 residues and phosphate groups. This interaction leads to the closed P-loop conformation in human thymidylate kinase, which promotes phosphorylation of nucleotides and has the potential as a model for novel compounds as a result of structure-based design studies.1-(5-O-Phosphono-2,3-dideoxy-β-D-glycero-penta-2-enofuranosyl)-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione запасные части и сырье
запасной предмет