格氏试剂（Grignard Reagent）是指分子式为RMgX的有机镁卤化物，是一类常用的金属有机试剂。主要用于大多数羰基化合物中引入烷基，转变成相应的醇。利用格氏试剂合成烃、醇、醛、酮、羧酸等一系列有机化合物的这些反应称格氏反应。
制备
卤烃在无水乙醚或四氢呋喃中与镁作用生成有机金属镁化合物。
# 格氏试剂非常活泼，可以和空气中的氧、水、二氧化碳发生反应。因此，在制备时，需保持干燥及隔绝空气。
# 活性顺序：
当卤素相同时，烯丙基卤代烃>叔卤代烷>仲卤代烷>伯卤代烷>卤代芳烃；
当烷基相同时，R-I > R-Br > R-Cl
# 由于碘代烷最贵，而氯代烷的反应性最差，所以，实验室中采用溴代烷来合成格氏试剂居多
反应机理
在反应液中格氏试剂不只是以RMgX的形式单独存在，而是R：Mg，MgX ，(RMgX)n等多种物质的混合物，各物质在溶液中存在动态平衡。
格氏试剂和羰基化合物的反应，可能是通过两种机理实现：极性反应机理和自由基单电子转移机理。
低电子亲核力的底物和格氏试剂反应是通常是经过环状过渡态进行协同反应。空间位阻较大的底物和大位阻格氏试剂（CMg键较弱）更倾向于进行自由基机理，格氏试剂向底物进行电子转移引发反应。
主要反应
产品列表
产品号 |
结构图 |
中文名称 |
规格 |
Cas |
包装 |
间甲苯基溴化镁溶液
1 M in Tetrahydrofuran
28987-79-3
100g,100mL,500mL,1L
仲丁基溴化镁
1M in Tetrahydrofuran
922-66-7
100g,500g
4-甲氧基-2-甲苯基溴化镁溶液
≧95%
148706-30-3
100mg
3-(三氟甲氧基)苯基溴化镁
0.5 M in THF
100mL
五氟苯基溴化镁
≧95%
879-05-0
100mL
3-溴苄基溴化镁 溶液
0.25M in THF
100mL
2,3-二甲基苯基溴化镁
0.5 M in THF
134640-85-0
100mL
（三甲基硅烷）甲基氯化镁溶液
1.0 M in diethyl ether
13170-43-9
100mL
2,5-二甲氧基苯基溴化镁 溶液
0.5 M in THF
62890-98-6
100mL
3-氟-4-甲基苯基溴化镁 溶液
0.5 M in THF
185077-02-5
100mL
2-甲基-1-萘基溴化镁
0.25 M solution in THF
21450-90-8
100mL
2,4-二甲氧基苯基溴化镁 溶液
0.5 M in THF
138109-49-6
100mL
十四烷基氯化镁
1.0 M solution in THF ,MkSeal
110220-87-6
100mL
5-氯-2-甲氧基苯基溴化镁
0.50M in THF
419535-75-4
100mL
4-异丁基苯基溴化镁
0.5M in THF
100mL
五亚甲基双(溴化镁) 溶液
23708-48-7
100mL
十八烷基氯化镁
0.5 M solution in THF
116980-66-6
100mL
5-氟-2-甲基苯基溴化镁
0.5 M solution in THF
186496-59-3
100mL
2,2-二甲基丙基氯化镁 溶液
1.0 M in THF
13132-23-5
100mL
4-氟-2-甲基苯基镁溴化物
0.5 M solution in THF
30897-90-6
100mL
4-(三氟甲氧基)苯基溴化镁
0.5 M in THF
169222-42-8
100mL
（三甲基硅烷）甲基氯化镁溶液
1mol/L in Tetrahydrofuran
13170-43-9
100mL
2-溴苄基溴化镁 溶液
0.25M in THF
56812-60-3
100mL
4-甲氧基苯基溴化镁
1M in THF
13139-86-1
100mL,500mL,1L
叔丁基氯化镁
1.0 M in THF
677-22-5
100mL,500mL,1L
异丁基氯化镁
2.0 M in THF
5674-02-2
100mL,500mL,1L
苯基溴化镁
1.0 M in THF
100-58-3
100mL,500mL,1L
戊基溴化镁溶液
1.0M in THF
693-25-4
100mL,500mL,1L
3-氯苯基溴化镁
0.5M solution in THF
36229-42-2
25mL,100mL,500mL
环戊基溴化镁
1mol/L in THF
33240-34-5
25mL,100mL,500mL,1L
辛基溴化镁溶液
2.0 M in diethyl ether
17049-49-9
100mL,500mL
烯丙基溴化镁
1.0 M in diethyl ether
1730-25-2
100mL,500mL
邻甲苯基溴化镁溶液
1.0 M in Tetrahydrofuran
932-31-0
100mL,500mL
仲丁基氯化镁
2.0M in THF
15366-08-2
100mL,500mL
3,5-二氟苯基溴化镁
0.5 M in THF
62351-47-7
100mL,500mL
十五烷基溴化镁
0.5 M solution in THF
78887-70-4
100mL,500mL
4-氟苯基溴化镁
1.0 M in MeTHF
352-13-6
100mL,500mL
烯丙基溴化镁
1.0M in THF
1730-25-2
100mL,500mL
环己基氯化镁溶液
1.0 M in 2-methyltetrahydrofuran
931-51-1
100mL,500mL
癸基溴化镁 溶液
1.0 M in diethyl ether
17049-50-2
100mL,500mL
异丙基氯化镁氯化锂络合物
1.3 M in THF
745038-86-2
100mL,500mL
2-甲氧苯基溴化镁溶液
1.0 M in 2-MeTHF
16750-63-3
100mL,500mL
3-戊烷溴化镁
2.0 M in diethyl ether
4852-26-0
100mL,500mL
甲基碘化镁
3.0 M in diethyl ether
917-64-6
100mL,500mL
十二烷基溴化镁 溶液
0.5 M in 2-methyltetrahydrofuran
15890-72-9
100mL,500mL
乙基氯化镁
2.0M solution in THF
2386-64-3
100mL,500mL,1L
1-丙炔溴化镁溶液
0.5 M in THF
16466-97-0
25mL,100mL,500mL
十二烷基溴化镁 溶液
1.0 M in diethyl ether
15890-72-9
100mL,500mL,800mL
甲基溴化镁
3.0 M solution in Diethyl ether
75-16-1
100mL,500mL,800mL
乙炔基溴化镁
0.5 M in THF
4301-14-8
100mL,500mL,800mL,1L
4-乙基苯基溴化镁 溶液
22873-28-5
50mL,100mL
3,4-二甲氧基苯基溴化镁
0.5 M solution in THF, MkSeal
89980-69-8
50mL,100mL
对甲苯基氯化镁
2.0 M solution in THF
696-61-7
100mL,800mL
己基溴化镁
1.0 M in THF
3761-92-0
100mL,250mL,500mL,800mL
2-萘溴化镁 溶液
0.5 M solution in THF
21473-01-8
100mL,500mL,800mL
3,5-双(三氟甲基)苯基溴化镁
0.5 M solution in THF
112981-69-8
100mL,500mL,800mL
苄基氯化镁
2.0 M in THF
6921-34-2
100mL,500mL,800mL
碘化镁乙醚络合物(易制毒)
0
29054-07-7
1g
乙炔基氯化镁溶液
0.5 M in THF
65032-27-1
1L
3-氟苯基溴化镁 溶液
1.0 M in THF
17318-03-5
100mL,500mL,1L
3-甲氧基苯基溴化镁
1.0M 四氢呋喃溶液
36282-40-3
100mL,500mL,1L
环丙基溴化镁
1mol/L in THF
23719-80-4
100mL,500mL,1L
3-丁烯溴化镁
0.5 M in THF
7103-09-5
100mL,500mL,1L
甲基溴化镁
1.0 M solution in THF
75-16-1
100mL,500mL,800mL,1L
对甲苯基溴化镁
1.0 M in THF
4294-57-9
100mL,500mL,800mL,1L
苯基氯化镁
2.0 M in tetrahydrofuran
100-59-4
100mL,500mL,1L
苄基氯化镁
1.0M in THF
6921-34-2
100mL,500mL,1L
异丙烯溴化镁
0.5 M in THF
13291-18-4
100mL,500mL,1L
异丙基溴化镁溶液
2.9M in 2-methyltetrahydrofuran
920-39-8
100mL,500mL,800mL,1L
异丙基溴化镁
1.0 M in THF
920-39-8
100mL,500mL,800mL,1L
异丙基氯化镁
2.0 M in THF
1068-55-9
100mL,250mL,500mL,800mL,1L
辛基溴化镁溶液
1.0M in Tetrahydrofuran
17049-49-9
250g
3,5-二甲苯基溴化镁
0.5M 四氢呋喃溶液
34696-73-6
250mL
丙基溴化镁
2M in THF
927-77-5
100mL,250mL
正丁基氯化镁
2.0 M in THF
693-04-9
100mL,250mL,500mL,1L
叔丁基氯化镁
2.0 M in diethyl ether
677-22-5
100mL,250mL,500mL
5-氯-2-噻吩基溴化镁
0.5 M solution in THF
111762-30-2
25mL,100mL
4-甲氧基苄基氯化镁
0.25 M in THF
38769-92-5
25mL,100mL
2,5-二甲基苯基溴化镁 (1M THF溶液)
2M in THF
30897-86-0
25mL,100mL,500mL
苄基溴化镁
1mol/L in THF
1589-82-8
25mL,100mL,500mL
2-甲基烯丙基氯化镁溶液
0.5 M in THF
5674-01-1
25mL,4×25mL,100mL,500mL,1L
丙基氯化镁
1.0M in MeTHF
2234-82-4
100mL,500mL
氯丙烯镁
1.0M in THF
2622-05-1
100mL,500mL
丙基氯化镁
2.0M in THF
2234-82-4
100mL,500mL
2-丁烯基氯化镁
0.5 M solution in THF
22649-70-3
100mL,500mL
1-甲基-2-丙烯基氯化镁 溶液
0.5 M in THF
21969-32-4
100mL,500mL
4-硫代苯甲醚溴化镁 溶液
0.5 M in THF
18620-04-7
100mL,500mL
乙基溴化镁
3.0 M in diethyl ether
925-90-6
100mL,500mL
环己基氯化镁
2.0 M in diethyl ether
931-51-1
100mL,500mL
2-甲基-2-苯丙基氯化镁 溶液
0.5 M in THF
35293-35-7
100mL,500mL
甲基碘化镁
1.0 M solution in THF
917-64-6
100mL,500mL
3-氟苯基溴化镁 溶液
1.0M in MeTHF
17318-03-5
100mL,500mL
1-辛基氯化镁
1.4 M solution in THF
38841-98-4
100mL,500mL
4-联苯溴化镁
0.5 M solution in THF
3315-91-1
100mL,500mL
己基溴化镁溶液
2.0 M in diethyl ether
3761-92-0
100mL,500mL
1-甲基-1-丙烯基溴化镁
0.5M 四氢呋喃溶液
85676-85-3
100mL,500mL
(环己基甲基)溴化镁
0.5 M solution in THF
35166-78-0
100mL,500mL
异丁基溴化镁溶液
1.0 M in THF
926-62-5
100mL,500mL
乙基溴化镁
1.0 M in THF
925-90-6
100mL,500mL,1L
邻甲苯基氯化镁
1.0M solution in THF
33872-80-9
100mL,500mL,1L
4-叔丁基苯基溴化镁
2.0 M in diethyl ether
63488-10-8
50mL,100mL,500mL
4-氟苄基氯化镁
0.25 M solution in diethyl ether
50mL,100mL,500mL,800mL
1-己基氯化镁溶液
2.0 M in THF
44767-62-6
100mL,500mL,800mL
甲基氯化镁 溶液
3.0 M in THF
676-58-4
100mL,500mL,1L
正庚基溴化镁
1.0 M in THF
13125-66-1
100mL,250mL,500mL,1L
3-联苯溴化镁
0.5M in THF
103068-18-4
25mL,100mL,500mL
环丙基溴化镁
0.5 M in THF
23719-80-4
25mL,100mL,500mL,1L
4-氟苄基氯化镁
0.25 M in THF
1643-73-8
50mL
3-氟-4-甲氧苯基溴化镁
0.5 M in THF
112780-67-3
50mL
3-氟苯基溴化镁 溶液
0.5 M in THF
17318-03-5
50mL
3-氯-5-氟苯基溴化镁 溶液
480438-50-4
50mL,100mL
4-氟-3-甲基苯基溴化镁溶液
1.0 M in THF
82297-89-0
50mL,100mL,500mL,800mL
1-萘基溴化镁
0.25 M in THF
703-55-9
5mL
甲基溴化镁
3.0 M solution in 2-Methyl-THF
75-16-1
100mL,500mL,800mL,1L
4-氟苯基溴化镁
1.0 M in THF
352-13-6
100mL,500mL,800mL,1L
氯乙烯基镁
1.6 M in THF
3536-96-7
100mL,500mL,800mL,1L
乙烯基溴化镁
1.0M in THF
1826-67-1
100mL,500mL,800mL,1L,
异丁基氯化镁
2.0 M solution in Diethyl ether
5674-02-2
25mL,800mL
4-叔丁基苯基溴化镁
0.5 M in THF
63488-10-8
100mL,500mL,800mL
2-甲基-1-丙烯基溴化镁 溶液
0.5 M in THF
38614-36-7
100mL,500mL,800mL
环己基溴化镁
1mol/L in THF
931-50-0
100mL,500mL,800mL,1L
乙基溴化镁
2.0 M solution in THF
925-90-6
100mL,500mL,800mL,1L
4-氯苯基溴化镁
1M in THF
873-77-8
100mL,500mL,800mL,1L
