The name of Novcaine
The Chinese name is Procaine
The English name is procaine
Chinese proletarian because alias hydrochloride | novocaine | amino ethyl 2-4 - aminobenzoic acid diethyl ester | 2 - (diethyl amino) ethyl - 4 - aminobenzoic acid ester | slave, because | 4 - aminobenzoic acid - 2 - ethyl ester (ethyl amino)
More English nicknames
Biological activity of novocaine
Procaine can exert local anesthetic activity through multiple targets.
Related category
Signal path > > Transmembrane transport > > GABA receptor
Signal path > > Neural signaling Pathway > > GABA receptor
Research Field > > neuropathy
Reference literature
[1]. Fan, P. and F.F. Weight, Procaine impairs the function of 5-HT3 receptor-ion channel complex in rat sensory ganglion neurons. Neuropharmacology, 1994. 33(12): p. 1573-9.
[2]. Villar-Garea, A., et al., Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells. Cancer Res, 2003. 63(16): p. 4984-9.
[3]. Adamec, R.E. and C. Stark-Adamec, The effects of procaine HCl on population cellular and evoked response activity within the limbic system of the cat. Evidence for differential excitatory action of procaine in a variety of limbic circuits. Prog Neuropsychopharmacol Biol Psychiatry, 1987. 11(4): p. 345-64.
Physical and chemical properties of novocaine
Density 1.1± 0.1g /cm3
Boiling point 373.6±22.0 °C at 760 mmHg
Melting point 61ºC
Molecular formula C13H20N2O2
Molecular weight 236.310
Flash point 179.8±22.3 °C
Accurate mass 236.152481
PSA 55.56000
LogP 2.36
Appearance character solid; White to Almost white powder to crystal
Vapor pressure 0.0±0.8 mmHg at 25°C
Refractive index 1.543
Water soluble in: ether, methanol, benzene, chloroform
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