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Triethylamine trihydrofluoride

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Triethylamine trihydrofluoride Basic information
Triethylamine trihydrofluoride Chemical Properties
  • Melting point:-29--27°C
  • Boiling point:70 °C15 mm Hg(lit.)
  • Density 0.989 g/mL at 25 °C(lit.)
  • refractive index n20/D 1.3915(lit.)
  • Flash point:190 °F
  • storage temp. Store below +30°C.
  • form Liquid
  • Specific Gravity0.989
  • color Clear yellow to brown
  • PH3 (H2O, 20℃)(saturated aqueous solution)
  • Water Solubility soluble
  • Sensitive Hygroscopic
  • BRN 5522945
  • CAS DataBase Reference73602-61-6(CAS DataBase Reference)
  • EPA Substance Registry SystemEthanamine, N,N-diethyl-, trihydrofluoride (73602-61-6)
Safety Information
MSDS
Triethylamine trihydrofluoride Usage And Synthesis
  • Application

    The t-butyldimethylsilyl (TBDMS) group is the most widely used 2'-OH protection in synthesis of oligoribonucleotides. The TBDMS-group became much used particularly after it was combined with phosphoroamidite methodology and was also the choice when H-phosphonate based RNA-synthesis was introduced. Removal of TBDMS-protection is most commonly done with 1 M tetrabutylammonium fluoride (TBAF) in tetrahydrofuran (THF). These conditions has proven efficient.

  • Chemical Propertiesclear yellow liquid
Triethylamine trihydrofluoride(73602-61-6)Related Product Information
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