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Doxofylline

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Doxofylline Basic information
Doxofylline Chemical Properties
  • Melting point:144-146°C
  • Boiling point:409.46°C (rough estimate)
  • Density 1.2896 (rough estimate)
  • refractive index 1.6000 (estimate)
  • RTECS XH5135000
  • pka0.42±0.70(Predicted)
  • Water Solubility Soluble
  • Merck 14,3438
  • CAS DataBase Reference69975-86-6(CAS DataBase Reference)
Safety Information
  • Hazard Codes Xi
  • Risk Statements 36/37/38
  • Safety Statements 26-36/37
  • HS Code 29399990
  • ToxicityLD50 in mice (mg/kg): 841 orally; 215.6 i.v.; in rats: 1022.4 orally, 445 i.p. (Franzone)
Doxofylline Usage And Synthesis
  • DescriptionDoxofylline, a xanthine bronchodilator related to theophylline, is useful in the treatment of asthma and similar bronchospastic disorders. It has minimal activity on intestinal smooth muscle and the cardiovascular system, and is reportedly devoid of the behavioral effects of theophylline.
  • OriginatorABC S.p.A. (Italy)
  • UsesH1 antihistamine
  • UsesDoxofylline is a xanthine molecule that appears to be both bronchodilator and anti-inflammatory with an improved therapeutic window over conventional xanthines such as Theophylline and the evidence su pporting the effects of Doxofylline in the treatment of lung diseases.
  • brand nameMaxivent (Roberts Pharmaceutical);ANSIMAR.
Doxofylline Preparation Products And Raw materials
Doxofylline(69975-86-6)Related Product Information
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