4-氰基-2-[[2-(4-氟-1-萘基)-1-氧代丙基]氨基]苯基丁酸
4-氰基-2-[[2-(4-氟-1-萘基)-1-氧代丙基]氨基]苯基丁酸
![4-氰基-2-[[2-(4-氟-1-萘基)-1-氧代丙基]氨基]苯基丁酸 结构式](https://img.chemicalbook.com/CAS/GIF/402473-54-5.gif)
4-氰基-2-[[2-(4-氟-1-萘基)-1-氧代丙基]氨基]苯基丁酸 性质
| 沸点 | 662.4±55.0 °C(Predicted) |
|---|---|
| 密度 | 1.30 |
| 储存条件 | -20°C |
| 溶解度 | DMSO 中≥40.4 mg/mL，温和加热；不溶于水； ≥8.1 mg/mL，乙醇溶液，温和加热和超声波 |
| 酸度系数(pKa) | 4.69±0.10(Predicted) |
| 形态 | 粉末 |
| 颜色 | 白色至米色 |
| InChI | InChI=1S/C24H21FN2O3/c1-15(18-11-12-21(25)20-7-3-2-6-19(18)20)24(30)27-22-13-16(14-26)9-10-17(22)5-4-8-23(28)29/h2-3,6-7,9-13,15H,4-5,8H2,1H3,(H,27,30)(H,28,29) |
| InChIKey | MTDIMKNAJUQTIO-UHFFFAOYSA-N |
| SMILES | C1(CCCC(O)=O)=CC=C(C#N)C=C1NC(=O)C(C1=C2C(C=CC=C2)=C(F)C=C1)C |
4-氰基-2-[[2-(4-氟-1-萘基)-1-氧代丙基]氨基]苯基丁酸 用途与合成方法
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EP4
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ONO-AE3-208 surpresses the in vitro cell invasion and migration in a dose-dependent manner without affecting cell proliferation. ONO-AE3-208 abolisheS CTGF in the presence of the EET synthesis inhibitor MS-PPOH. Arachidonic acid (AA) causeS dose-dependent dilation of the attached Af-Art, and this effect is blocked by ONO-AE3-208.
ONO-AE3-208 surpresses the in vivo bone metastasis of PC3 cells in mice. The photon tumor burdens are significantly increased in a time-dependent manner in the control group in comparison with those in the ONO-AE3-208-treated group. The rate of metastasis formation is significantly higher in the former than in the latter. The median time of metastasis formation is 29 d in the ONO-AE3-208-treated animals as compared with 21 d in the controls.
4-氰基-2-[[2-(4-氟-1-萘基)-1-氧代丙基]氨基]苯基丁酸 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026-09-15 | HY-50901 | 4-氰基-2-[[2-(4-氟-1-萘基)-1-氧代丙基]氨基]苯基丁酸 | 402473-54-5 | 1 mg | 444 |
| 2026-09-15 | HY-50901 | 4-氰基-2-[[2-(4-氟-1-萘基)-1-氧代丙基]氨基]苯基丁酸 | 402473-54-5 | 2mg | 620 |
