Basic information Safety Related Supplier
ChemicalBook >  Product Catalog >  Chemical Reagents >  Organic reagents >  Esters >  Methyl ester compound >  Trimethyl orthobenzoate

Trimethyl orthobenzoate

Basic information Safety Related Supplier
Trimethyl orthobenzoate Basic information
Trimethyl orthobenzoate Chemical Properties
Safety Information
MSDS
Trimethyl orthobenzoate Usage And Synthesis
  • Chemical Propertiesclear colorless liquid
  • UsesTrimethyl Orthobenzoate is a reagent used in the synthesis of quinazolines. Also used in the prepaaration of nintedanib (N478290), used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.
  • Synthesis Reference(s)Journal of the American Chemical Society, 72, p. 1661, 1950 DOI: 10.1021/ja01160a067
  • General Description
    Trimethyl orthobenzoate reacts with P-dimethylaminophosphonic acid bis(1-methylhydrazide) to yield 1,2,5,6-tetrahydro-1,5-dimethyl-6-(N,N-dimethylamino)-6-phenyl-1,2,4,5,6-tetrazaphosphorine-6-oxide.
Trimethyl orthobenzoate(707-07-3)Related Product Information
Trimethyl orthobenzoateSupplierMore
  • Company Name:Beijing Taiya Jie Technology Development Co., Ltd. Gold
  • Tel:13552411790 021-33690831-8001
  • Email:postmaster@tyjchem.cn;1094628792@qq.com
  •  
  • Company Name:Qingdao Sanrenxing Chemical Co., Ltd. Gold
  • Tel:18505321860
  • Email:qdsrxchem@163.com
  •  
  • Company Name:Jinan XuanDe Chemical Co., Ltd. Gold
  • Tel:18866891188 0531-88803958-
  • Email:xuandechem@126.com
  •  
  • Company Name:Chongqing Xingcan Pharmaceutical Technology Co., Ltd. Gold
  • Tel:15223382610
  • Email:xingcanyaoye@sina.com;
  •  
  • Company Name:J & K SCIENTIFIC LTD.
  • Tel:400-666-7788 010-82848833-
  • Email:jkinfo@jkchemical.com;market6@jkchemical.com
  •