Dimethyl 2,6-Pyridinedicarboxylate

Off-White Solid

Dimethyl 2,6-pyridinedicarboxylate may be used in the synthesis of:

• ditopic macrocycle having two xylyl rings linked by diethylene glycol and 2,6-pyridinediamide spacers, which acts as host molecule capable of forming complexes with diphenylurea derivatives
• N,N′-bis(2-aminoethyl)dipicoloinic acid diamide Schiff base
• 1,1′-(2,6-bispyridyl)bis-3-(9-ethylcarbazole-3-yl)-1,3-propanedione

Dimethyl 2,6-pyridinedicarboxylate could be used as a starting material to synthesize four pyridine-bridged bis pyrazole ligands by Claisen condensation[1]. These ligands could be further treated with UCl₄ to yield the corresponding novel mononuclear uranium(IV) complexes [U^IV(R′′′₂L)(Cl)₄].    

The standard molar enthalpy of formation for dimethyl 2,6-pyridinedicarboxylate (dimethylpyridine-2,6-dicarboxylate) has been calculated from the standard molar enthalpy of combustion, which was measured by a static bomb calorimeter.

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

[1] Korzekwa, Jana , et al. "Synthesis and characterization of uranium(IV) tetrachloro complexes in bis-pyrazolylpyridine ligand environments." Dalton Transactions (2017):10.1039.C7DT02947K.