Guanosine, 7-methylguanylyloxyphosphinicooxyphosphinico-(5'→5')-2'-O-methyladenylyl-(3'→5')-, inner salt

3'OMe-m7GpppAmpG is a trinucleotide Cap analogue. 3'OMe-m7GpppAmpG shows a significant translational efficiency. 3'OMe-m7GpppAmpG can be used as a potential molecular biology tool in the field of mRNA vaccines and mRNA transfection, such as protein production, gene therapy and anti-cancer immunization[1].

[1] Senthilvelan A, et al. Trinucleotide Cap Analogue Bearing a Locked Nucleic Acid Moiety: Synthesis, mRNA Modification, and Translation for Therapeutic Applications. Org Lett. 2021 Jun 4;23(11):4133-4136. DOI:10.1021/acs.orglett.1c01037