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Vitamin E succinate

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Vitamin E succinate Basic information
Vitamin E succinate Chemical Properties
  • Melting point:~76 °C(lit.)
  • Boiling point:625.8±55.0 °C(Predicted)
  • Density 1.002±0.06 g/cm3(Predicted)
  • storage temp. 2-8°C
  • solubility Practically insoluble in water, very soluble in methylene chloride, soluble in acetone and in anhydrous ethanol.
  • form neat
  • pka4.35±0.17(Predicted)
  • λmax286nm(EtOH)(lit.)
  • Merck 14,9495
  • BRN 4038233
  • CAS DataBase Reference4345-03-3(CAS DataBase Reference)
  • EPA Substance Registry SystemD-.alpha.-Tocopheryl acid succinate (4345-03-3)
Safety Information
  • WGK Germany 1
  • RTECS EJ9984000
  • 8-10-23
  • HS Code 2936280000
  • ToxicityLD50 oral in rat: > 7gm/kg
MSDS
Vitamin E succinate Usage And Synthesis
  • Chemical PropertiesOff-White to Pale Yellow Solid
  • UsesA potent antioxidant tocopherol
  • UsesA potent novel antineoplastic agent with high selectivity and cooperativity with tumor necrosis factor-related apoptosis-inducing ligand (Apo2 ligand). It inhibits proliferation of mesothelioma cells by selective down-regulation of fibroblast growth factor receptors. Furthermore, it has been shown to enhance the anti-tumor effect of dendritic cell vaccines.
  • General DescriptionWhite powder.
  • Air & Water ReactionsInsoluble in water.
  • Reactivity ProfileVitamin E succinate is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.
  • Fire HazardFlash point data for Vitamin E succinate are not available; however, Vitamin E succinate is probably combustible.
  • Safety ProfileWhen heated to decomposition it emits acrid smoke and irritating fumes.
Vitamin E succinate(4345-03-3)Related Product Information
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