178908-09-3
中文名称:178908-09-3
英文名称:UK-240455
CAS号:178908-09-3
分子式:C11H11Cl2N3O5S
分子量:368.19
EINECS号:
Mol文件:178908-09-3.mol
178908-09-3 性质
密度 | 1.686±0.06 g/cm3(Predicted) |
---|---|
储存条件 | Store at -20°C |
溶解度 | 溶于二甲基亚砜 |
酸度系数(pKa) | 7.96±0.20(Predicted) |
178908-09-3 用途与合成方法
UK-240455 是一个有效且有选择性的 N-甲基 D-天冬氨酸 (NMDA) 甘氨酸位点上的拮抗剂。
NMDA
UK-240455 is a potent and selective N-methyl D-aspartate (NMDA) glycine site antagonist. Following i.v. administration of UK-240455 to male rats, UK-240455 has a clearance of 12 mL/min/kg and a volume of distribution of 0.4 L/kg. The plasma concentration of UK-240455 decreases with an apparent half-life of 0.4 h. Analysis of urine (0 to 24 h) for unchanged UK-240455 indicates that 57% of the dose administered is excreted unchanged in the urine. The urinary clearance of UK-240455 in the rat is therefore 7 mL/min/kg. Following oral administration of UK-240455 to male rats, the apparent elimination half-life of UK-240455 from plasma following oral administration is 1.6 h.
178908-09-3供应商 更多
天津普西唐生物医药科技有限公司
联系电话:010-60605840 15801484223
产品介绍:
英文名称:UK-240455
CAS:178908-09-3
包装信息:1mg
备注: 试剂级
TargetMol中国(陶术生物)
联系电话: 4008200310
产品介绍:
中文名称:化合物UK-240455
英文名称:UK-240455
CAS:178908-09-3
纯度:99.70%
包装信息:1 mg;5 mg;10 mg;25 mg;50 mg;100 mg