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Androstenedione

Basic information Biological Metabolism Safety Related Supplier
Androstenedione Basic information
Androstenedione Chemical Properties
  • Melting point:170-171 °C(lit.)
  • Boiling point:368.77°C (rough estimate)
  • alpha D30 +199° (in chloroform)
  • Density 1.0655 (rough estimate)
  • refractive index 1.4709 (estimate)
  • Flash point:2℃
  • storage temp. Controlled Substance, -20°C Freezer
  • color Dimorphous: Needles from acetone, or crystalsfrom hexane
  • Water Solubility 57.28mg/L(25 ºC)
  • Merck 13,643
  • InChIKeyAEMFNILZOJDQLW-QAGGRKNESA-N
  • CAS DataBase Reference63-05-8(CAS DataBase Reference)
  • NIST Chemistry ReferenceAndrost-4-ene-3,17-dione(63-05-8)
  • EPA Substance Registry System4-Androstenedione (63-05-8)
Safety Information
MSDS
Androstenedione Usage And Synthesis
  • Biological MetabolismThe in vitro perfusion of the human placental lobule with 7-ethoxycoumarin gives 7-hydroxycoumarin, and perfusion with androstenedione gives the conversion products, estrone, estradiol, and testosterone. The human placenta has only a limited capacity for the metabolism of xenobiotics.
  • Chemical PropertiesWhite to Off-White Solid
  • UsesTestosterone precursor and metabolite with androgenic activity. Controlled substance (anabolic sterid)
  • DefinitionChEBI: A 3-oxo Delta4-steroid that is androst-4-ene substituted by oxo groups at positions 3 and 17. It is a steroid hormone synthesized in the adrenal glands and gonads.
  • Safety ProfileAn experimental teratogen. Otherexperimental reproductive effects. Questionablecarcinogen with experimental tumorigenic data. Whenheated to decomposition it emits acrid smoke andirritating fumes.
  • Purification MethodsCrystallise the dione from hexane. It is soluble in *C6H6, CHCl3 and EtOH. It has max at 239nm. It is a precursor of estrone or testosterone and has androgenic activity. [Ruzicka & Wettstein Helv Chim Acta 18 980 1935, Beilstein 7 III 3636, 7 IV 2381.]
Androstenedione Preparation Products And Raw materials
Androstenedione(63-05-8)Related Product Information
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