基本属性 生物活性靶点体内研究 用途与合成方法 217799-03-6 价格(试剂级) 供应商

217799-03-6

217799-03-6

中文名称:217799-03-6
英文名称:KP496
CAS号:217799-03-6
分子式:C31H34ClN3O7S3
分子量:692.27
EINECS号:
Mol文件:217799-03-6.mol
217799-03-6 结构式

217799-03-6 性质

沸点 847.9±75.0 °C(Predicted)
密度 1.378±0.06 g/cm3(Predicted)
储存条件 Store at -20°C
溶解度 溶于二甲基亚砜
酸度系数(pKa) 3.09±0.36(Predicted)

217799-03-6 用途与合成方法

KP49 是一个有选择性的 Leukotriene D4 and Thromboxane A2 受体的双重拮抗剂。

LTD 4

TXA 2 Receptor

KP496 significantly inhibits acute (day 7) and chronic (day 21) lung inflammation. KP496 attenuates the number of lymphocytes on day 7 and those of macrophages, neutrophils, and eosinophils on days 7 and 21. KP496 and prednisolone significantly suppress the increase of hydroxyl-L-proline content in the lung. Compare to respective vehicle control group, the inhibition ratio of KP496 and prednisolone for increase of hydroxyl-L-proline content is about 74 and 63%, respectively. The KP496 (100 mg/head) group and prednisolone (10 mg/kg) group exhibit significant inhibition of numbers of infiltrating total cells, eosinophils, monocytes/macrophages, and lymphocytes compare with the control group. Infiltration of all types of cells except neutrophils is decreased in the KP496 (30m g/head) group, though not to significant extents.

217799-03-6 价格(试剂级)

更新日期 产品编号 产品名称 CAS号 包装 价格
2024-04-30 HY-U00253 1 mg 4500
2024-01-25 HY-U00253 217799-03-6 217799-03-6 5mg 8500

217799-03-6供应商 更多

TargetMol中国(陶术生物)
联系电话: 4008200310
产品介绍:
中文名称:化合物 T11764
英文名称:KP496;KP496,KP-496
CAS:217799-03-6
纯度:98%
包装信息:5 mg
苏州美石生物科技有限公司
联系电话: 1173954148q
产品介绍:
英文名称:217799-03-6
CAS:217799-03-6
纯度:99% HPLC
包装信息:1G;5G;10G;100G;1KG;
备注:医药级