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Etoposide Structure

Etoposide

Chemical Properties

Melting point 236-251 °C (lit.)
Boiling point 563.9°C (rough estimate)
alpha  D20 -110.5° (c = 0.6 in chloroform)
Density  1.2966 (rough estimate)
refractive index  -110.5 ° (C=0.6, CHCl3)
storage temp.  2-8°C
solubility  DMSO: 30 mg/mL
form  powder
pka 9.8(at 25℃)
color  white
Water Solubility  Insoluble in water.
Merck  14,3886
BCS Class 4
Stability Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months
IARC 1 (Vol. 76, 100A) 2012, 1 (Vol. 76, 100A) 2012
EPA Substance Registry System Etoposide (33419-42-0)

Safety Information

Hazard Codes  T,Xi
Risk Statements  45-22-36/37/38
Safety Statements  53-45-36/37-26
RIDADR  3249
WGK Germany  3
RTECS  KC0190000
HazardClass  6.1(a)
PackingGroup  II
HS Code  29389090
Hazardous Substances Data 33419-42-0(Hazardous Substances Data)
Toxicity LD50 oral in rabbit: 147mg/kg

MSDS

Usage And Synthesis

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