FIPI (3 mg/kg; intraperitoneal injection; 2 times) shows protective effect in carotid thrombosis model and ischemic stroke model[4].
| Animal Model: | Ferric chloride (HY-Y0266) or transient middle cerebral artery occlusion treated mice[4] |
| Dosage: | 3 mg/kg |
| Administration: | Intraperitoneal injection (i.p.); 2 times, 12 h apart |
| Result: | Delayed the thrombus formation and only 3 of 9 vessels occluded during the 30-minute observation period in arterial thrombosis models.
Reduced the infarct volumes, improved motor and overall nerve function and did not impair normal hemostasis in ischemic stroke models. |
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