(+)-8-(2-Hydroxy-3-methyl-3-butenyl)-7-methoxy-2H-1-benzopyran-2-one

Auraptenol possesses robust antidepressant-like efficacy in mice. Auraptenol attenuates vincristine-induced mechanical hyperalgesia through serotonin 5-HT1A receptors, it has potential to be a novel analgesic for the management of neuropathic pain. 3. Auraptenol shows high inhibitory activities against larval settlement of Balanus albicostatus with EC50values of 3.38 ug m/L.

Auraptenol is a coumarin that can be isolated from the leaves of Murraya paniculata[1].

5-HT Receptor

[1] IMAI, F., et al. Constituents of the leaves of Murraya paniculata collected in Taiwan. CHEMICAL & PHARMACEUTICAL BULLETIN, 37(2), 358–362.