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EST

Basic information Safety Related Supplier
EST Basic information
  • Product Name:EST
  • CAS:88321-09-9
  • MF:C17H30N2O5
  • MW:342.43
  • EINECS:
  • Mol File:88321-09-9.mol
EST Chemical Properties
  • Melting point:126.2°C
  • Boiling point:477.88°C (rough estimate)
  • Density 1.0657 (rough estimate)
  • refractive index 1.5800 (estimate)
  • storage temp. -20°C
  • solubility Soluble in DMSO, DMF or ethanol
  • form White solid
  • color Fine needles from EtOH
Safety Information
  • Hazard Codes Xi
  • Risk Statements 36/37/38
  • Safety Statements 26-36-24/25
  • RIDADR 3077
  • WGK Germany 2
  • RTECS RR0404300
  • HS Code 29242990
  • Toxicitycyt-ham:lng 200 mg/L IYKEDH 17,815,86
MSDS
EST Usage And Synthesis
  • UsesE-64d is an inhibitor of cathepsins B and L as well as a potential inhibitor of calpain. E-64d has been shown to inhibit lysosomal proteases. E-64d has been used in combination with Prepstatin A to in terfere with autolysosomal digestion. E-64d displays neurovascular and neuronal protective effects after focal cerebral ischemia in rats.
  • DefinitionChEBI: An L-leucine derivative that is the amide obtained by formal condensation of the carboxy group of (2S,3S)-3-(ethoxycarbonyl)oxirane-2-carboxylic acid with the amino group of N-(3-methylb tyl)-L-leucinamide.
  • Safety ProfileModerately toxic by intraperitoneal route. An experimental teratogen. Experimental reproductive effects. Mutation data reported. Whenheated to decomposition it emits toxic fumes of NOx.
EST(88321-09-9)Related Product Information
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  • Company Name:Dalian Meilun Biotech Co., Ltd. Gold
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  • Company Name:Alabiochem Tech.Co., Ltd.
  • Tel:13962259467 0512-58900862
  • Email:sales@alabiochem.com;sales@alabiochem.com
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